Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.

Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice.

Parafibromin, a transcription factor associated with the PAF complex, is encoded by the HRPT2 gene, mutations of which cause the hyperparathyroidism-jaw tumor syndrome (OMIM145001). To elucidate the function of parafibromin, we generated conventional and conditional Hrpt2 knockout mice and found tha...

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מידע ביבליוגרפי
Main Authors: Wang, P, Bowl, MR, Bender, S, Peng, J, Farber, L, Chen, J, Ali, A, Zhang, Z, Alberts, A, Thakker, R, Shilatifard, A, Williams, B, Teh, B
פורמט: Journal article
שפה:English
יצא לאור: 2008

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