Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

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<p><strong>Background</strong> Accurately quantifying the risk of osteoporotic fracture is important for directing appropriate clinical interventions. While skeletal measures such as heel quantitative speed of sound (SOS) and dual-energy X-ray absorptiometry bone mineral density ar...

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Bibliographic Details
Main Authors: Lu, T, Forgetta, V, Keller-Baruch, J, Nethander, M, Bennett, D, Forest, M, Bhatnagar, S, Walters, RG, Lin, K, Chen, Z, Li, L, Karlsson, M, Mellström, D, Orwoll, E, McCloskey, EV, Kanis, JA, Leslie, WD, Clarke, RJ, Ohlsson, C, Greenwood, CMT, Richards, JB
Format: Journal article
Language:English
Published: BMC 2021

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