Targeting MAIT cells as a cellular adjuvant for humoral immunity: a new player in a very old game
In this article, I discuss recent work by Pankhurst et al. They found that MAIT cells can serve as a cellular adjuvant to boost immunity to a protein adjuvant. Intranasal co-administration of protein antigen with a strong MAIT cell ligand results in the the production of mucosal IgA and IgG antibody...
Hovedforfatter: | Provine, NM |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Wiley
2023
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Lignende værker
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MAIT cells in health and disease
af: Provine, NM, et al.
Udgivet: (2020) -
Human MAIT cell activation in vitro
af: Hagel, JP, et al.
Udgivet: (2019) -
Augmentation of vaccine-induced humoral and cellular immunity by a physical radiofrequency adjuvant
af: Yan Cao, et al.
Udgivet: (2018-09-01) -
MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity
af: Theresa E. Pankhurst, et al.
Udgivet: (2023-04-01) -
Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
af: Garner, LC, et al.
Udgivet: (2023)