Targeting MAIT cells as a cellular adjuvant for humoral immunity: a new player in a very old game
In this article, I discuss recent work by Pankhurst et al. They found that MAIT cells can serve as a cellular adjuvant to boost immunity to a protein adjuvant. Intranasal co-administration of protein antigen with a strong MAIT cell ligand results in the the production of mucosal IgA and IgG antibody...
Үндсэн зохиолч: | Provine, NM |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Wiley
2023
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Ижил төстэй зүйлс
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MAIT cells activate dendritic cells to promote TFH cell differentiation and induce humoral immunity
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Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity
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