Association of malaria parasite population structure, HLA, and immunological antagonism.

Host-parasite coevolution has been likened to a molecular arms race, with particular parasite genes evolving to evade specific host defenses. Study of the variants of an antigenic epitope of Plasmodium falciparum that induces a cytotoxic T cell response supports this view. In African children with m...

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Bibliographic Details
Main Authors: Gilbert, S, Plebanski, M, Gupta, S, Morris, J, Cox, M, Aidoo, M, Kwiatkowski, D, Greenwood, B, Whittle, H, Hill, A
Format: Journal article
Language:English
Published: 1998