Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: a prospective study.

BACKGROUND: An acquired V617F mutation in JAK2 occurs in most patients with polycythaemia vera, but is seen in only half those with essential thrombocythaemia and idiopathic myelofibrosis. We aimed to assess whether patients with the mutation are biologically distinct from those without, and why th...

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Main Authors: Campbell, P, Scott, L, Buck, G, Wheatley, K, East, C, Marsden, J, Duffy, A, Boyd, E, Bench, A, Scott, M, Vassiliou, G, Milligan, D, Smith, SR, Erber, W, Bareford, D, Wilkins, B, Reilly, J, Harrison, C, Green, A
格式: Journal article
语言:English
出版: 2005