Immunogenicity and efficacy of Zika virus envelope domain III in DNA, protein, and ChAdOx1 adenoviral-vectored vaccines

Immunogenicity and efficacy of Zika virus envelope domain III in DNA, protein, and ChAdOx1 adenoviral-vectored vaccines

The flavivirus envelope protein domain III (EDIII) was an effective immunogen against dengue virus (DENV) and other related flaviviruses. Whether this can be applied to the Zika virus (ZIKV) vaccinology remains an open question. Here, we tested the efficacy of ZIKV-EDIII against ZIKV infection, usin...

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Bibliographic Details
Main Authors: López-Camacho, C, De Lorenzo, G, Slon-Campos, JL, Dowall, S, Abbink, P, Larocca, RA, Kim, YC, Poggianella, M, Graham, V, Findlay-Wilson, S, Rayner, E, Carmichael, J, Dejnirattisai, W, Boyd, M, Hewson, R, Mongkolsapaya, J, Screaton, GR, Barouch, DH, Burrone, OR, Patelm AH, Reyes-Sandoval, A
Format: Journal article
Language:English
Published: MDPI 2020

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