Modulation of indoleamine 2,3-dioxygenase by interferon-gamma in human placental chorionic villi.

The effect of interferon-gamma on indoleamine 2,3-dioxygenase, a tryptophan catabolizing enzyme, was studied in cultured human placental chorionic villi. The activity of indoleamine 2,3-dioxygenase was markedly stimulated by interferon-gamma in a time- and concentration-dependent manner. Interferon-...

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Bibliographic Details
Main Authors: Kudo, Y, Boyd, C, Sargent, I, Redman, C
Format: Journal article
Language:English
Published: 2000