Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.

Activation of invariant CD1d-dependent NK T cells (iNKT cells) in vivo through administration of the glycolipid ligand alpha-galactosylceramide (alpha-GalCer) or the sphingosine-truncated alpha-GalCer analog OCH leads to CD40 signaling as well as the release of soluble molecules including type 1 and...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Silk, J, Hermans, I, Gileadi, U, Chong, T, Shepherd, D, Salio, M, Mathew, B, Schmidt, R, Lunt, S, Williams, K, Stratford, I, Harris, A, Cerundolo, V
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2004