Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.
Activation of invariant CD1d-dependent NK T cells (iNKT cells) in vivo through administration of the glycolipid ligand alpha-galactosylceramide (alpha-GalCer) or the sphingosine-truncated alpha-GalCer analog OCH leads to CD40 signaling as well as the release of soluble molecules including type 1 and...
Prif Awduron: | , , , , , , , , , , , , |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2004
|