Inducible expression of the cell surface heparan sulfate proteoglycan syndecan-2 (fibroglycan) on human activated macrophages can regulate fibroblast growth factor action.

Monocyte/macrophages play important roles in regulating tissue growth and angiogenesis through the controlled release of heparin-binding growth factors such as fibroblast growth factor (FGF), vascular endothelial growth factor, and heparin binding epidermal growth factor. The action of these potent...

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Bibliographic Details
Main Authors: Clasper, S, Vekemans, S, Fiore, M, Plebanski, M, Wordsworth, P, David, G, Jackson, D
Format: Journal article
Language:English
Published: 1999