Enhanced ER Ca2+ store filling by overexpression of SERCA2b promotes IP3-evoked puffs.
Liberation of Ca(2+) from the endoplasmic reticulum (ER) through inositol trisphosphate receptors (IP(3)R) is modulated by the ER Ca(2+) content, and overexpression of SERCA2b to accelerate Ca(2+) sequestration into the ER has been shown to potentiate the frequency and amplitude of IP(3)-evoked Ca(2...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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