Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum.

The malaria parasite Plasmodium falciparum has a great capacity for evolutionary adaptation to evade host immunity and develop drug resistance. Current understanding of parasite evolution is impeded by the fact that a large fraction of the genome is either highly repetitive or highly variable and th...

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Bibliographic Details
Main Authors: Miles, A, Iqbal, Z, Vauterin, P, Pearson, R, Campino, S, Theron, M, Gould, K, Mead, D, Drury, E, O'Brien, J, Ruano Rubio, V, MacInnis, B, Mwangi, J, Samarakoon, U, Ranford-Cartwright, L, Ferdig, M, Hayton, K, Su, X, Wellems, T, Rayner, J, McVean, G, Kwiatkowski, D
Format: Journal article
Language:English
Published: Cold Spring Harbor Laboratory Press 2016