Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.
For viruses to establish persistent infections in their hosts, they must possess some mechanism for evading clearance by the immune system. When inoculated into adult immunocompetent mice, wild-type lymphocytic choriomeningitis virus (LCMV ARM) induces a CD8(+)-mediated cytotoxic T lymphocyte (CTL)...
| Main Authors: | , , |
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| Format: | Journal article |
| Jezik: | English |
| Izdano: |
1991
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