The role of current product release criteria for identification of human islet preparations suitable for clinical transplantation.
BACKGROUND: Alloimmunity, autoimmunity, and nonspecific inflammation are known to be potential determinants for long-term islet survival and insulin independence. Sufficient islet mass is a key determinant. But islet engraftment and posttransplant survival may also depend on functional characteristi...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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