The role of current product release criteria for identification of human islet preparations suitable for clinical transplantation.

BACKGROUND: Alloimmunity, autoimmunity, and nonspecific inflammation are known to be potential determinants for long-term islet survival and insulin independence. Sufficient islet mass is a key determinant. But islet engraftment and posttransplant survival may also depend on functional characteristi...

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Bibliographic Details
Main Authors: Eckhard, M, Brandhorst, D, Winter, D, Jaeger, C, Jahr, H, Bretzel, R, Brendel, MD
Format: Journal article
Language:English
Published: 2004