Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.

The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead campaigns. One such public set is explored, employing an open source research mechan...

Full description

Bibliographic Details
Main Authors: Williamson, A, Ylioja, P, Robertson, M, Antonova-Koch, Y, Avery, V, Baell, J, Batchu, H, Batra, S, Burrows, J, Bhattacharyya, S, Calderon, F, Charman, S, Clark, J, Crespo, B, Dean, M, Debbert, S, Delves, M, Dennis, A, Deroose, F, Duffy, S, Fletcher, S, Giaever, G, Hallyburton, I, Gamo, F, Gebbia, M, Guy, R, Hungerford, Z, Kirk, K, Lafuente-Monasterio, M, Lee, A, Meister, S, Nislow, C, Overington, J, Papadatos, G, Patiny, L, Pham, J, Ralph, S, Ruecker, A, Ryan, E, Southan, C, Srivastava, K, Swain, C, Tarnowski, M, Thomson, P, Turner, P, Wallace, I, Wells, T, White, K, White, L, Willis, P, Winzeler, E, Wittlin, S, Todd, M
Format: Journal article
Language:English
Published: American Chemical Society 2016

Similar Items