Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.

Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation.

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Complex interplay between T helper (Th) cells and macrophages contributes to the formation and progression of atherosclerotic plaques. While Th1 cytokines promote inflammatory activation of lesion macrophages, Th2 cytokines attenuate macrophage-mediated inflammation and enhance their repair function...

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Bibliographic Details
Main Authors: Vats, D, Mukundan, L, Odegaard, J, Zhang, L, Smith, K, Morel, C, Wagner, R, Greaves, D, Murray, P, Chawla, A
Format: Journal article
Language:English
Published: 2006

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