Absence of effects of prolonged simvastatin therapy on nocturnal sleep in a large randomized placebo-controlled study. Oxford Cholesterol Study Group.

1. It has been suggested that lipophilic HMG CoA reductase inhibitors, like lovastatin and simvastatin, may cause sleep disturbance. 2. Six hundred and twenty-one patients at increased risk of coronary heart disease were randomized in a single centre to receive 40 mg daily simvastatin, 20 mg daily s...

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Bibliographic Details
Main Authors: Keech, A, Armitage, J, Wallendszus, K, Lawson, A, Hauer, A, Parish, S, Collins, R
Format: Journal article
Language:English
Published: 1996