Lack of a significant adverse cardiovascular effect of combined quinine and mefloquine therapy for uncomplicated malaria.
Quinine dihydrochloride (10 mg salt/kg infused over one hour) and mefloquine (15 mg base/kg) were given simultaneously to 13 adults with uncomplicated falciparum malaria. Supine and standing blood pressures were recorded and the electrocardiogram monitored. Plasma concentrations of the 2 drugs were...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
1997
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