Tuning the formation of a covalent haem-protein link by selection of reductive or oxidative conditions as exemplified by ascorbate peroxidase.
Previous work [Metcalfe, Ott, Patel, Singh, Mistry, Goff and Raven (2004) J. Am. Chem. Soc. 126, 16242-16248] has shown that the introduction of a methionine residue (S160M variant) close to the 2-vinyl group of the haem in ascorbate peroxidase leads to the formation of a covalent haem-methionine li...
Главные авторы: | Metcalfe, C, Daltrop, O, Ferguson, S, Raven, E |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
2007
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