Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.

ATP-sensitive potassium channels (K-ATP channels) couple cell metabolism to electrical activity and are important in the physiology and pathophysiology of many tissues. In pancreatic beta-cells, K-ATP channels link changes in blood glucose concentration to insulin secretion. They are also the target...

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Váldodahkkit: Tucker, S, Gribble, F, Zhao, C, Trapp, S, Ashcroft, F
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 1997