Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
The synthesis and inhibitory potencies of a novel series of 3,5-diaryl-1H-pyrazoles as specific inhibitors of prokaryotic arylamine N-acetyltransferase enzymes is described. The series is based on hit compound 1 3,5-diaryl-1H-pyrazole identified from a high-throughout screen that has been carried ou...
Κύριοι συγγραφείς: | Fullam, E, Talbot, J, Abuhammed, A, Westwood, I, Davies, S, Russell, A, Sim, E |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2013
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
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Structure and mechanism of arylamine N-acetyltransferases.
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Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
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Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
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Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
ανά: Fullam, E, κ.ά.
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