Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
The synthesis and inhibitory potencies of a novel series of 3,5-diaryl-1H-pyrazoles as specific inhibitors of prokaryotic arylamine N-acetyltransferase enzymes is described. The series is based on hit compound 1 3,5-diaryl-1H-pyrazole identified from a high-throughout screen that has been carried ou...
मुख्य लेखकों: | Fullam, E, Talbot, J, Abuhammed, A, Westwood, I, Davies, S, Russell, A, Sim, E |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2013
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समान संसाधन
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Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.
द्वारा: Fullam, E, और अन्य
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Structure and mechanism of arylamine N-acetyltransferases.
द्वारा: Westwood, I, और अन्य
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Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars.
द्वारा: Westwood, I, और अन्य
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Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
द्वारा: Sim, E, और अन्य
प्रकाशित: (2008) -
Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.
द्वारा: Fullam, E, और अन्य
प्रकाशित: (2009)