Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.

Multi-subunit Cullin-RING E3 ligases often use repeat domain proteins as substrate-specific adaptors. Structures of these macromolecular assemblies are determined for the F-box-containing leucine-rich repeat and WD40 repeat families, but not for the suppressor of cytokine signaling (SOCS)-box-contai...

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Autori principali: Muniz, JR, Guo, K, Kershaw, N, Ayinampudi, V, von Delft, F, Babon, J, Bullock, A
Natura: Journal article
Lingua:English
Pubblicazione: 2013