Selective permeabilization of the blood-brain barrier at sites of metastasis

BACKGROUND: Effective chemotherapeutics for primary systemic tumors have limited access to brain metastases because of the blood-brain barrier (BBB). The aim of this study was to develop a strategy for specifically permeabilizing the BBB at sites of cerebral metastases. METHODS: BALB/c mice were inj...

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Autori principali: Sibson, N, Vallis, K, Hamilton, A, Seymour, L, Anthony, D, Connell, J, Chatain, G
Natura: Journal article
Lingua:English
Pubblicazione: Oxford University Press 2013