The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

Homodimerization is an essential step for membrane type 1 matrix metalloproteinase (MT1-MMP) to activate proMMP-2 and to degrade collagen on the cell surface. To uncover the molecular basis of the hemopexin (Hpx) domain-driven dimerization of MT1-MMP, a crystal structure of the Hpx domain was solved...

Bibliográfalaš dieđut
Váldodahkkit:	Tochowicz, A, Goettig, P, Evans, R, Visse, R, Shitomi, Y, Palmisano, R, Ito, N, Richter, K, Maskos, K, Franke, D, Svergun, D, Nagase, H, Bode, W, Itoh, Y
Materiálatiipa:	Journal article
Giella:	English
Almmustuhtton:	2011

Geahča maid

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