The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions.

Homodimerization is an essential step for membrane type 1 matrix metalloproteinase (MT1-MMP) to activate proMMP-2 and to degrade collagen on the cell surface. To uncover the molecular basis of the hemopexin (Hpx) domain-driven dimerization of MT1-MMP, a crystal structure of the Hpx domain was solved...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Tochowicz, A, Goettig, P, Evans, R, Visse, R, Shitomi, Y, Palmisano, R, Ito, N, Richter, K, Maskos, K, Franke, D, Svergun, D, Nagase, H, Bode, W, Itoh, Y
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: 2011