The Ugi four-component reaction enables expedient synthesis and comparison of photoaffinity probes

Photoaffinity probes are increasingly being used for the study of biological interactions; however, the lack of structure-activity relationship studies has hindered their rational application. We describe the use of the Ugi four-component reaction (U-4CR) for the expedient and versatile assembly of...

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Bibliographic Details
Main Authors: Bush, J, Walport, L, McGouran, J, Leung, I, Berridge, G, van Berkel, S, Basak, A, Kessler, B, Schofield, C
Format: Journal article
Language:English
Published: 2013