Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and agonist major histocompatibility complex (MHC)-peptide complexes, and elevation of cytoplasmic Ca2+ is observed within seconds of the first detect...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2005
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