Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

T cell receptor (TCR) microclusters form within seconds of T cell contact with supported planar bilayers containing intercellular adhesion molecule-1 and agonist major histocompatibility complex (MHC)-peptide complexes, and elevation of cytoplasmic Ca2+ is observed within seconds of the first detect...

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Detalles Bibliográficos
Autores principales: Campi, G, Varma, R, Dustin, M
Formato: Journal article
Lenguaje:English
Publicado: 2005