Thromboxane A2 inhibition of SKCa after NO synthase block in rat middle cerebral artery.

BACKGROUND AND PURPOSE: NO/prostanoid independent, EDHF-mediated hyperpolarization and dilation in rat middle cerebral arteries is mediated solely by endothelial cell IK(Ca). However, when the NO-pathway is also active, both SK(Ca) and IK(Ca) contribute to EDHF responses. As the SK(Ca) component ca...

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Bibliographic Details
Main Authors: McNeish, A, Garland, C
Format: Journal article
Language:English
Published: 2007