LysNDeNovo: an algorithm enabling de novo sequencing of Lys-N generated peptides fragmented by electron transfer dissociation.

Recently, we introduced a novel proteomics method employing a metalloendopeptidase with Lys-N specificity to produce proteolytic peptides. Fragmentation spectra generated by electron transfer dissociation, for a large proportion of the Lys-N proteolytic peptides, were found to be dominated by extens...

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Bibliographic Details
Main Authors: van Breukelen, B, Georgiou, A, Drugan, M, Taouatas, N, Mohammed, S, Heck, A
Format: Journal article
Language:English
Published: 2010