Novel insights into actions of bisphosphonates on bone: differences in interactions with hydroxyapatite.

Bisphosphonates are now the most widely used drugs for diseases associated with increased bone resorption, such as osteoporosis. Although bisphosphonates act directly on osteoclasts, and interfere with specific biochemical processes such as protein prenylation, their ability to adsorb to bone minera...

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Autors principals: Nancollas, G, Tang, R, Phipps, R, Henneman, Z, Gulde, S, Wu, W, Mangood, A, Russell, R, Ebetino, F
Format: Journal article
Idioma:English
Publicat: 2006