Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes.

The transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal body and the axoneme that regulates ciliary traffic. Mutations in genes encoding TZ proteins (TZPs) cause human inherited diseases (ciliopathies). Here, we use the trypanosome to identify TZ comp...

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Bibliographic Details
Main Authors: Dean, S, Moreira-Leite, F, Varga, V, Gull, K
Format: Journal article
Language:English
Published: National Academy of Sciences 2016