Cilium transition zone proteome reveals compartmentalization and differential dynamics of ciliopathy complexes.

The transition zone (TZ) of eukaryotic cilia and flagella is a structural intermediate between the basal body and the axoneme that regulates ciliary traffic. Mutations in genes encoding TZ proteins (TZPs) cause human inherited diseases (ciliopathies). Here, we use the trypanosome to identify TZ comp...

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Hlavní autoři: Dean, S, Moreira-Leite, F, Varga, V, Gull, K
Médium: Journal article
Jazyk:English
Vydáno: National Academy of Sciences 2016