From pioneer to repressor: bimodal foxd3 activity dynamically remodels neural crest regulatory landscape in vivo

The neural crest (NC) is a transient embryonic stem cell populations characterised by its multipotency and broad developmental potential. Here, we perform NC-specific transcriptional and epigenomic profiling of foxd3-mutant versus wild-type cells in vivo to define the gene regulatory circuits contro...

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Bibliographic Details
Main Authors: Lukoseviciute, M, Gavriouchkina, D, Williams, R, Hochgreb-Hagele, T, Senanayake, U, Chong-Morrison, V, Thongjuea, S, Repapi, E, Mead, A, Sauka-Spengler, T
Format: Journal article
Published: Cell Press 2018