Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.

OBJECTIVE: Type 2 diabetes is characterized by impaired pancreatic beta-cell function and decreased insulin sensitivity. Genome-wide association studies have identified common, novel type 2 diabetes susceptibility loci within the FTO, CDKAL1, CDKN2A/CDKN2B, IGF2BP2, HHEX/IDE, and SLC30A8 gene region...

Full description

Bibliographic Details
Main Authors:	Pascoe, L, Tura, A, Patel, S, Ibrahim, I, Ferrannini, E, Zeggini, E, Weedon, M, Mari, A, Hattersley, A, McCarthy, M, Frayling, T, Walker, M
Format:	Journal article
Language:	English
Published:	2007

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function.

Similar Items