Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

The enteric nervous system (ENS) predominantly originates from vagal neural crest (VNC) cells that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...

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Dades bibliogràfiques
Autors principals:	Ling, ITC, Sauka-Spengler, T
Format:	Journal article
Idioma:	English
Publicat:	Springer Nature 2019
Matèries:	CRISPR-Cas systems Gene regulatory networks Developmental biology Epigenomics Transcriptional regulatory elements

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