Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

The enteric nervous system (ENS) predominantly originates from vagal neural crest (VNC) cells that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...

書誌詳細
主要な著者:	Ling, ITC, Sauka-Spengler, T
フォーマット:	Journal article
言語:	English
出版事項:	Springer Nature 2019
主題:	CRISPR-Cas systems Gene regulatory networks Developmental biology Epigenomics Transcriptional regulatory elements

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