Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages

The enteric nervous system (ENS) predominantly originates from vagal neural crest (VNC) cells that emerge from the caudal hindbrain, invade the foregut and populate the gastrointestinal tract. However, the gene regulatory network (GRN) orchestrating the early specification of VNC remains unknown. Us...

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Những tác giả chính:	Ling, ITC, Sauka-Spengler, T
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Springer Nature 2019
Những chủ đề:	CRISPR-Cas systems Gene regulatory networks Developmental biology Epigenomics Transcriptional regulatory elements

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