The notch ligand JAGGED1 as a target for anti-tumor therapy.

The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence, pan-Notch inhibitors and therapeutic antibodies targeting one or more of the Notch receptor...

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Những tác giả chính: Li, D, Masiero, M, Banham, A, Harris, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Frontiers Research Foundation 2014