The notch ligand JAGGED1 as a target for anti-tumor therapy.
The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence, pan-Notch inhibitors and therapeutic antibodies targeting one or more of the Notch receptor...
Những tác giả chính: | , , , |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
Frontiers Research Foundation
2014
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