Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.

Diabetes, obesity and Alzheimer’s disease (AD) are associated with vascular complications and impaired nitric oxide (NO) production. Furthermore, increased β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1), APP and β-amyloid (Aβ) are linked with vascular disease development and raised...

Full description

Bibliographic Details
Main Authors:	Meakin, PJ, Coull, BM, Tuharska, Z, McCaffery, C, Akoumianakis, I, Antoniades, C, Brown, J, Griffin, KJ, Platt, F, Ozber, CH, Yuldasheva, NY, Makava, N, Skromna, A, Prescott, AR, McNeilly, AD, Siddiqui, MK, Palmer, CNA, Khan, F, Ashford, MLJ
Format:	Journal article
Language:	English
Published:	American Society for Clinical Investigation 2020

Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.

Similar Items