The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

Instructive programmes guiding cell-fate decisions in the developing mouse embryo are controlled by a few so-termed master regulators. Genetic studies demonstrate that the T-box transcription factor Eomesodermin (Eomes) is essential for epithelial-to-mesenchymal transition, mesoderm migration and sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Costello, I, Pimeisl, I, Dräger, S, Bikoff, E, Robertson, E, Arnold, S
Formato: Journal article
Lenguaje:English
Publicado: 2011