Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis.

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis.

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To clarify the role of common genetic variation in the Interleukin-1β (IL1B) and Interleukin-1R antagonist (IL1RN) genes on risk of knee and hip osteoarthritis (OA) and severity of knee OA by means of large-scale meta-analyses.

Bibliographic Details
Main Authors: Kerkhof, H, Doherty, M, Arden, N, Abramson, S, Attur, M, Bos, S, Cooper, C, Dennison, E, Doherty, SA, Evangelou, E, Hart, D, Hofman, A, Javaid, M, Kerna, I, Kisand, K, Kloppenburg, M, Krasnokutsky, S, Maciewicz, R, Meulenbelt, I, Muir, K, Rivadeneira, F, Samuels, J, Sezgin, M, Slagboom, E, Smith, A
Format: Journal article
Language:English
Published: 2011

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