Investigating checkpoint inhibitor-induced gastrointestinal disease: comparisons with idiopathic ulcerative colitis and health
In the last decade, immunotherapy with anti-PD1 and anti-CTLA4 drugs has revolutionized the treatment of metastatic cancer. A significant proportion of patients given these checkpoint inhibitors develop off-target inflammation in the colon (checkpoint inhibitor-induced colitis, CC). Ulcerative colit...
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Format: | Thesis |
Language: | English |
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2022
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