Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression

Neurochemical markers of amyotrophic lateral sclerosis (ALS) that reflect underlying disease mechanisms might help in diagnosis, staging and prediction of outcome. We aimed at determining the origin and differential diagnostic and prognostic potential of the putative marker of microglial activation...

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Main Authors:	Steinacker, P, Verde, F, Fang, L, Feneberg, E, Oeckl, P, Roeber, S, Anderl-Straub, S, Danek, A, Diehl-Schmid, J, Fassbender, K, Fliessbach, K, Foerstl, H, Giese, A, Jahn, H, Kassubek, J, Kornhuber, J, Landwehrmeyer, G, Lauer, M, Pinkhardt, E, Prudlo, J, Rosenbohm, A, Schneider, A, Schroeter, M, Tumani, H, Von Arnim, C, Weishaupt, J, Weydt, P, Ludolph, A, Yilmazer Hanke, D, Otto, M, Ftldc Study Group
Format:	Journal article
Language:	English
Published:	BMJ Publishing Group 2017

Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression

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