A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

Interactions with commensal microbes shape host immunity on multiple levels and play a pivotal role in human health and disease. Tissue-dwelling, antigen-specific T cells are poised to respond to local insults, making their phenotype important in the relationship between host and microbes. Here we s...

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Bibliographic Details
Main Authors: Hackstein, C-P, Costigan, D, Drexhage, L, Pearson, C, Bullers, S, Ilott, N, Akther, HD, Gu, Y, FitzPatrick, MEB, Harrison, OJ, Garner, LC, Mann, EH, Pandey, S, Friedrich, M, Provine, NM, Uhlig, HH, Marchi, E, Powrie, F, Klenerman, P, Thornton, EE
Format: Journal article
Language:English
Published: Springer Nature 2022