Tagged mutagenesis by efficient Minos-based germ line transposition.

Germ line gene transposition technology has been used to generate "libraries" of flies and worms carrying genomewide mutations. Phenotypic screening and DNA sequencing of such libraries provide functional information resulting from insertional events in target genes. There is also a great...

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Bibliographic Details
Main Authors: de Wit, T, Dekker, S, Maas, A, Breedveld, G, Knoch, T, Langeveld, A, Szumska, D, Craig, R, Bhattacharya, S, Grosveld, F, Drabek, D
Format: Journal article
Language:English
Published: 2010