Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

Hypertension is a heritable and major contributor to the global burden of disease. The sum of rare and common genetic variants robustly identified so far explain only 1%-2% of the population variation in BP and hypertension. This suggests the existence of more undiscovered common variants. We conduc...

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Main Authors:	Padmanabhan, S, Melander, O, Johnson, T, Di Blasio, A, Lee, W, Gentilini, D, Hastie, C, Menni, C, Monti, M, Delles, C, Laing, S, Corso, B, Navis, G, Kwakernaak, A, van der Harst, P, Bochud, M, Maillard, M, Burnier, M, Hedner, T, Kjeldsen, S, Wahlstrand, B, Sjogren, M, Fava, C, Montagnana, M, Danese, E, Torffvit, O, Hedblad, B, Snieder, H, Connell, J, Brown, M, Samani, N, Farrall, M, Cesana, G, Mancia, G, Signorini, S, Grassi, G, Eyheramendy, S, Wichmann, H, Laan, M, Strachan, D, Sever, P, Shields, D, Stanton, A, Vollenweider, P, Teumer, A, Volzke, H, Rettig, R, Newton-Cheh, C, Arora, P, Zhang, F, Soranzo, N, Spector, T, Lucas, G, Kathiresan, S, Siscovick, D, Luan, J, Loos, R, Wareham, N, Penninx, B, Nolte, I, McBride, M, Miller, W, Nicklin, SA, Baker, A, Graham, D, McDonald, R, Pell, J, Sattar, N, Welsh, P, Munroe, P, Caulfield, M, Zanchetti, A, Dominiczak, A
Format:	Journal article
Language:	English
Published:	Public Library of Science 2010

Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

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