Accurately reflecting uncertainty when using patient-level simulation models to extrapolate clinical trial data
<p><strong>Introduction:</strong> Patient-level simulation models facilitate extrapolation of clinical trial data while allowing for heterogeneity, prior history, and nonlinearity. However, combining different types of uncertainty around within-trial and extrapolated results remain...
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
SAGE Publications
2020
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