Evidence for successive peptide binding and quality control stages during MHC class I assembly

<p>Intracellular antigens are continually presented to cytotoxic T lymphocytes by major histocompatibility complex (MHC) class I molecules, which consist of a polymorphic 43 kDa heavy chain and a 12 kDa soluble subunit <em>β</em>2-microglobulin (<em>β</em>2m), and which...

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Bibliographic Details
Main Authors: Lewis, J, Elliott, T
Format: Journal article
Language:English
Published: Current Biology Ltd. 1998
Subjects: