Evidence for successive peptide binding and quality control stages during MHC class I assembly
<p>Intracellular antigens are continually presented to cytotoxic T lymphocytes by major histocompatibility complex (MHC) class I molecules, which consist of a polymorphic 43 kDa heavy chain and a 12 kDa soluble subunit <em>β</em>2-microglobulin (<em>β</em>2m), and which...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
Current Biology Ltd.
1998
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Subjects: |