Genetic contribution to radiographic severity in osteoarthritis of the knee.

OBJECTIVE: Knee osteoarthritis (OA) has a significant genetic component. The authors have assessed the role of three variants reported to influence risk of knee OA with p<5×10-8 in determining patellofemoral and tibiofemoral Kellgren Lawrence (K/L) grade in knee OA cases. METHODS: 3474 knee O...

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Bibliographic Details
Main Authors: Valdes, A, Doherty, S, Muir, K, Zhang, W, Maciewicz, R, Wheeler, M, Arden, N, Cooper, C, Doherty, M
Format: Journal article
Language:English
Published: 2012